Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary central nervous system lymphoma: CT and pathologic correlation.

Y Y Lee, J M Bruner, P Van Tassel

    AJR. American Journal of Roentgenology
    |October 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP.

    Oncogene·2010
    Same author

    The treatment of war injuries of the hand in the U.S. Army.

    Journal. Iowa State Medical Society·2010
    Same author

    The descriptive epidemiology of craniopharyngioma.

    Neurosurgical focus·2007
    Same author

    TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation.

    Apoptosis : an international journal on programmed cell death·2005
    Same author

    Genetic abnormalities in oligodendroglial and ependymal tumours.

    Journal of neurology·2002
    Same author

    Imaging findings after radiotherapy to the pelvis.

    AJR. American journal of roentgenology·2001
    Same journal

    The Banality of Cancer: Entropy As a Third Pillar of Lung Nodule Risk Assessment.

    AJR. American journal of roentgenology·2026
    Same journal

    A Narrow Window for Artificial Intelligence-Generated Synthetic Temporal Bone CT From MRI.

    AJR. American journal of roentgenology·2026
    Same journal

    From Uncertainty to Actionable Management: The Isolated Abnormal Axillary Lymph Node.

    AJR. American journal of roentgenology·2026
    Same journal

    Beyond Detection: Translating Artificial Intelligence-Driven Opportunistic Screening Into Clinical Action.

    AJR. American journal of roentgenology·2026
    Same journal

    Navigating PSMA PET Radiopharmaceuticals: Clinical and Operational Factors.

    AJR. American journal of roentgenology·2026
    Same journal

    From Mesenteric Ischemia to Intestinal Stroke.

    AJR. American journal of roentgenology·2026
    See all related articles

    CT scans reveal distinct patterns in primary central nervous system (CNS) lymphoma. AIDS patients frequently show ring enhancement, mimicking abscesses, necessitating accurate tissue diagnosis for effective treatment.

    Area of Science:

    • Neuroradiology
    • Oncology
    • Infectious Diseases

    Background:

    • Primary central nervous system (CNS) lymphoma is a rare malignancy.
    • Distinguishing CNS lymphoma from other brain lesions, such as abscesses, can be challenging on CT imaging.
    • Acquired immunodeficiency syndrome (AIDS) is associated with an increased incidence of CNS lymphoma.

    Purpose of the Study:

    • To evaluate the variable CT patterns of primary CNS lymphoma.
    • To correlate CT findings with histopathologic findings.
    • To identify differences in CT appearance between AIDS and non-AIDS patients with CNS lymphoma.

    Main Methods:

    • Retrospective review of CT findings in 15 patients with histologically proven primary CNS lymphoma.
    • Pathologic correlation of CT observations.

    Related Experiment Videos

  • Analysis of lesion characteristics including density, enhancement pattern, and surrounding edema.

    • Main Results:

    • Most lesions in non-AIDS patients were hyper- or isodense, round/oval masses with homogeneous enhancement and edema, showing preserved lymphoma cells without necrosis.
    • In AIDS patients, rim or ring enhancement was frequent, mimicking brain abscess, with extensive tumor necrosis and peripheral viable cells.
    • An infrequent pattern included multiple infiltrative nonnodular solid enhancements with extensive edema and infiltrating viable tumor cells.

    Conclusions:

    • CT patterns of primary CNS lymphoma vary, particularly in AIDS patients.
    • Ring-enhancing lesions in AIDS patients can represent either lymphoma or abscess, highlighting the need for tissue diagnosis.
    • Accurate diagnosis through tissue collection is crucial for appropriate treatment of CNS lymphoma.