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Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
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Recent advances in self-adjuvanting glycoconjugate vaccines

Yoshiyuki Manabe1, Tsung-Che Chang2, Koichi Fukase1

  • 1Department of Chemistry, Graduate School of Science, Osaka University, Japan; Core for Medicine and Science Collaborative Research and Education, Project Research Center for Fundamental Sciences, Graduate School of Science, Osaka University, Japan.

Drug Discovery Today. Technologies
|December 13, 2021
PubMed
Summary

Self-adjuvanting vaccines link antigens to adjuvants for enhanced immune responses. This approach avoids toxic adjuvants and improves vaccine efficacy, positioning them as next-generation vaccines.

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