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Updated: Oct 10, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Comprehensive mitral valve prolapse assessment by cardiovascular MRI
F Musella1, A Azzu2, A S Antonopoulos3
1Department of Advanced Biomedical Sciences, University Federico II of Naples. Naples, Italy.
Cardiovascular magnetic resonance imaging (CMRI) enhances understanding and risk assessment of mitral valve prolapse (MVP). This review details CMRI
Area of Science:
- Cardiovascular Imaging
- Cardiac MRI
- Valvular Heart Disease
Background:
- Mitral valve prolapse (MVP) is a common yet incompletely understood valvular heart disorder.
- Advances in cardiovascular magnetic resonance imaging (CMRI) have improved MVP assessment.
- Understanding MVP pathophysiology is crucial for patient management and risk stratification.
Purpose of the Study:
- To review recent insights into mitral valve prolapse (MVP) pathophysiology.
- To highlight the emerging role of cardiovascular magnetic resonance imaging (CMRI) in MVP diagnosis and risk assessment.
- To provide a practical CMRI protocol for MVP assessment.
Main Methods:
- Review of recent scientific literature on mitral valve prolapse (MVP).
- Focus on cardiovascular magnetic resonance imaging (CMRI) techniques and findings.
- Discussion of emerging concepts like mitral annular disjunction (MAD) and myocardial fibrosis.
Main Results:
- CMRI offers detailed assessment of MVP, improving understanding of its pathophysiology.
- Emerging concepts include mitral annular disjunction (MAD) and the link between fibrosis, arrhythmia, and sudden death.
- CMRI is valuable for both diagnosis and risk stratification in MVP patients.
Conclusions:
- Cardiovascular magnetic resonance imaging (CMRI) is pivotal in advancing the understanding and management of mitral valve prolapse (MVP).
- The review proposes a comprehensive CMRI protocol for practical clinical application.
- CMRI aids in identifying patients at risk for adverse outcomes like arrhythmia and sudden death.
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