Related Experiment Video
Updated: Oct 10, 2025
07:17
Production and Detection of Reactive Oxygen Species ROS in Cancers
Published on: November 21, 2011
70.4K
Reactive Oxygen Species: Do They Play a Role in Adaptive Immunity?
Esen Yonca Bassoy1,2, Michael Walch3, Denis Martinvalet4,5
1International Society of Liver Surgeons (ISLS), Cankaya Ankara, Turkey.
Frontiers in Immunology
|December 13, 2021
Summary
Reactive oxygen species (ROS) play a role in adaptive immunity, influencing T-cell biology. This review explores ROS functions in T cells and considers their potential impact on B cells.
Area of Science:
- Immunology
- Cell Biology
Background:
- The immune system distinguishes self from non-self using innate and adaptive defenses.
- Innate immunity provides rapid defense via barriers, cells, and inflammation.
- Adaptive immunity involves T and B lymphocytes for pathogen elimination and memory.
Purpose of the Study:
- To review the role of reactive oxygen species (ROS) in adaptive immunity.
- To examine ROS contributions to T-cell biology.
- To discuss potential ROS roles in B-cell biology.
Main Methods:
- Literature review focusing on reactive oxygen species in adaptive immunity.
- Analysis of existing research on ROS in T-cell function.
- Exploration of evidence for ROS involvement in B-cell responses.
Main Results:
- Reactive oxygen species are implicated in various immune responses, particularly innate immunity.
- ROS influence T-cell biology, contributing to immune cell functions.
- The specific roles of ROS in B-cell biology require further investigation.
Conclusions:
- Reactive oxygen species are integral to adaptive immune processes, especially T-cell functions.
- Further research is needed to fully elucidate the impact of ROS on B-cell immunity.
More Related Videos
13:20Flow Cytometric Measurement Of ROS Production In Macrophages In Response To FcγR Cross-linking
Published on: March 7, 2019
16.1K
10:05Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
Published on: May 8, 2020
2.0K
Related Concept Videos
01:29Oxygen Requirements and Growth Patterns
438
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
438
01:20Special Features of Adaptive Immunity
1.3K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
1.3K
01:27Redox Reactions
323
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
323
01:23Cells of the Adaptive Immune Response
5.5K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
5.5K
01:22T Cell Activation and Clonal Selection
8.3K
T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
Naive T cells that have not yet encountered an antigen express two primary CD...
8.3K
01:28Inflammatory Response
11.2K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
11.2K