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Nerve Graft and Nerve Transfer for Improving Elbow Flexion in Children with Obstetric Palsy. A Systematic Review
Eduardo Velásquez-Girón1, James A Zapata-Copete2
1Seção de Cirurgia Ortopédica de Mão, Departamento de Cirurgia, Universidad del Valle, Cali, Colômbia.
Insights
Nerve graft and nerve transfer are equally effective for improving elbow flexion in newborns with obstetric brachial plexus palsy. This systematic review highlights both as viable options for nerve reconstruction in affected children.
Area of Science:
- Pediatric Surgery
- Neurology
- Orthopedics
Background:
- Obstetric brachial plexus palsy is a common newborn injury from birth-related traction.
- It significantly impacts arm function, particularly elbow flexion.
Purpose of the Study:
- To systematically review nerve graft and nerve transfer procedures for improving elbow flexion in children with obstetric brachial plexus palsy.
- To compare the efficacy of these two surgical interventions.
Main Methods:
- Systematic review following PRISMA guidelines.
- Searched multiple databases (MEDLINE, EMBASE, LILACS, Cochrane, Web of Science, Wholis, SCOPUS).
- Included clinical trials, quasi-experiments, and cohort studies of children (≤ 3 years) with obstetric palsy undergoing nerve graft or transfer.
Main Results:
- Seven studies were included; three compared nerve graft versus nerve transfer, and four combined them.
- Both nerve graft and nerve transfer demonstrated equal improvement in elbow flexion based on the Medical Research Council grading system.
- Both techniques are equally effective for nerve reconstruction in obstetric palsy.
Conclusions:
- Nerve graft and nerve transfer are equally beneficial for restoring elbow flexion in obstetric brachial plexus palsy.
- Further research, especially randomized clinical trials, is recommended to validate these findings.
Abstract:
Obstetric brachial plexus palsy is a rather common injury in newborns, caused by traction to the brachial plexus during labor. In this context, with the present systematic review, we aimed to explore the use of nerve graft and nerve transfer as procedures to improve elbow flexion in children with obstetric palsy. For the present review, we followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the MEDLINE, EMBASE, LILACS, The Cochrane Central Register of Controlled Trials, Web of Science, Wholis and SCOPUS databases. Predetermined criteria defined the following requirements for inclusion of a study: Clinical trials, quasi-experiments, and cohort studies that performed nerve graft and nerve transfer in children (≤ 3 years old) with diagnosis of obstetric palsy. The risk of bias in nonrandomized studies of interventions assessment tool was used for nonrandomized studies. Out of seven studies that used both procedures, three of them compared the procedures of nerve graft with nerve transfer, and the other four combined them as a reconstructive method for children with obstetric palsy. According to the Medical Research Council grading system, both methods improved equally elbow flexion in the children. Overall, our results showed that both techniques of nerve graft and nerve transfer are equally good options for nerve reconstruction in cases of obstetric palsy. More studies approaching nerve reconstruction techniques in obstetric palsy should be made, preferably randomized clinical trials, to validate the results of the present systematic review.
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