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Updated: Jul 19, 2026

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
Published on: March 25, 2016
COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
Nadine El Kassis1, Wael Abdallah1, Rim Abou Chakra1
1Department of Gynecology & Obstetrics, Hôtel-Dieu de France University Hospital, Saint Joseph University, Beirut, 116-5137, Lebanon.
Aim:
Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2.
Case Presentation:
We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontaneous labor. She was delivered by cesarean section after dynamical dystocia. Placental cord blood was retrieved immediately and sent to evaluate the titers of COVID-19 antibodies. Vaccine-generated antibodies were present in the umbilical cord with IgG spike >100 AU/ml.
Conclusion:
By reviewing the literature, vaccination seems to give hope about the potential protective effect of the maternal vaccination on her baby. Thus, pregnant women deserve a priority in the COVID-19 vaccination program.
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