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A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices

Christina Stefanaki1, George Kontochristopoulos1, Eleni Hatzidimitraki2

  • 1Pediatric Dermatology Clinic, Andreas Sygros University Skin Hospital, Athens, Greece.

Skin Appendage Disorders
|December 13, 2021
PubMed

Insights

Alopecia areata (AA) in children typically presents mildly, often on the scalp. Potent topical steroids are the most effective treatment for promoting hair regrowth in pediatric cases.

Area of Science:

  • Pediatric Dermatology
  • Dermatology
  • Autoimmune Diseases

Background:

  • Alopecia areata (AA) frequently affects children, but data on its clinical features and treatment are limited.
  • Understanding pediatric AA is crucial for effective management.

Purpose of the Study:

  • To analyze the clinical characteristics of alopecia areata in children.
  • To evaluate treatment choices and outcomes for pediatric alopecia areata.

Main Methods:

  • Retrospective review of pediatric dermatology records over 12 years.
  • Inclusion of 364 children diagnosed with alopecia areata aged 1-12 years.
  • Collection of clinical data, treatment regimens, and follow-up information.

Main Results:

  • The majority of pediatric AA cases (90.7%) presented with scalp patches; severe forms (totalis/universalis) were rare.
  • Topical steroids were the primary treatment (69.1%), followed by topical steroids with minoxidil (14.3%).
  • Potent topical and intralesional steroids showed the best results for hair regrowth, which was treatment-dependent (p=0.003).

Conclusions:

  • Pediatric alopecia areata commonly manifests as a mild form.
  • Potent topical steroids are the recommended mainstay treatment for childhood alopecia areata.
Abstract

Keywords:
Alopecia areataMalesMinoxidilOphiasisTopical steroids

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