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Published on: August 2, 2011
First complete genome characterization of duck plague virus from India
Ashutosh Aasdev1, Satyam D Pawar1,2, Anamika Mishra1
1Pathogenomics Lab, ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh 462022 India.
Abstract:
In this study, we report the complete genome sequencing of the Duck plague virus from India for the first time. The sequencing was done on the MinION nanopore sequencer from Oxford Nanopore Technologies. The closest relative is the European strain 2085v, with 99.98 and 99.8% identity at the amino acid and nucleotide level respectively. Moreover, 72 out of 77 ORFs are completely conserved between the 2 strains. The high similarity with the European strain over the only three other pathogenic strains reported from China points to the circulation of European strain in India. The fly pathways of migratory birds and co-habitation with native species being a probable reason. More complete genome data from diverse sampling locations are needed to characterize the genomic features, develop diagnostics, vaccines, and understand the evolution of the virus.

