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Updated: Oct 10, 2025
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
A case of pancreatic carcinosarcoma detected on PET/CT
Lingxiao Cheng1, Yao Liu, Cen Lou
1Department of Nuclear Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3, East Qingchun Road, Hangzhou 310016, China. chenglingxiao2017@zju.edu.cn, chenglingxiao22@126.com.
Abstract:
Primary pancreatic carcinosarcoma is a rare and malignant neoplasm composed of a mixture of sarcomatous and carcinomatous elements. With fewer than forty cases ever reported, the recognition of this rare phenomenon can be difficult. In the present case, a 73-year-old woman with pancreatitis underwent computed tomography which revealed wall-off pancreatic necrosis. Following initial and delayed fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed high uptake of tracer in pancreatic mass, endoscopic biopsy revealed carcinosarcoma. The patient underwent laparoscopic pancreato-caudal resection and was confirmed to have pancreatic carcinosarcoma on microscopic evaluation. The case shows the importance of PET/CT on the early diagnosis in pancreatic mass, and suggests pancreatic carcinosarcoma should be considered as a possible differential diagnosis, which can hasten treatment and improve patient outcomes.
