Related Experiment Video
Updated: Oct 10, 2025
08:45
Glass-Based Devices to Generate Drops and Emulsions
Published on: April 5, 2022
2.9K
Controllable Droplet Ejection of Multiple Reagents through Focused Acoustic Beams
Qing Guo1, Mengchuan Shao2, Xiao Su1
1State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China.
Langmuir : the ACS Journal of Surfaces and Colloids
|December 14, 2021
Summary
This study introduces a new method for acoustic droplet ejection (ADE) to precisely control fluid transfer. By analyzing reagent properties, this technique enhances efficiency and accuracy in biochemical research applications.
Area of Science:
- Biochemistry
- Fluid Dynamics
- Materials Science
Background:
- Acoustic droplet ejection (ADE) offers contactless and rapid fluid transfer.
- Precise control of droplet velocity is crucial for accurate detection and coalescence.
- Current ADE power control methods are inefficient and time-consuming.
Purpose of the Study:
- To develop a novel, efficient method for controlling multiple reagent ejection in ADE systems.
- To predict and adjust droplet initial velocity based on fluid properties.
Main Methods:
- Analyzing the relationship between the product of kinematic viscosity and surface tension and droplet initial velocity.
- Developing a predictive model for input power adjustment in ADE.
- Experimental validation using dimethyl sulfoxide and polystyrene microspheres.
Main Results:
- The proposed method allows for controllable ejection of multiple reagents.
- Experimental results for dimethyl sulfoxide droplet velocity showed good agreement with predictions (error < 8%).
- Successfully constructed an ADE system for continuous dispensing of cell surrogates.
Conclusions:
- The new method significantly improves the precision and efficiency of ADE fluid handling.
- This advancement provides a valuable tool for biochemical research and other fields requiring precise liquid handling.
- The predictive power control method optimizes ADE system performance for various reagents.
