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Updated: Oct 10, 2025

In Vivo Imaging Systems IVIS Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
A case report of ChAdOx1 nCoV-19 vaccine-associated encephalitis
Junko Takata1, Simon M Durkin2, Solomon Wong3
1Department of Infectious Diseases and Tropical Medicine, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, Harrow, HA1 3UJ, UK.
Background:
Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis.
Case Presentation:
A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes.
Conclusions:
This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.
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