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Updated: Oct 10, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Enhancing Microbiome Research through Genome-Scale Metabolic Modeling
Nana Y D Ankrah1, David B Bernstein2, Matthew Biggs3
1State University of New York at Plattsburgh, Plattsburgh, New York, USA.
Abstract:
Construction and analysis of genome-scale metabolic models (GEMs) is a well-established systems biology approach that can be used to predict metabolic and growth phenotypes. The ability of GEMs to produce mechanistic insight into microbial ecological processes makes them appealing tools that can open a range of exciting opportunities in microbiome research. Here, we briefly outline these opportunities, present current rate-limiting challenges for the trustworthy application of GEMs to microbiome research, and suggest approaches for moving the field forward.
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