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Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

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[Erythrodermic psoriasis after COVID-19].

Jeta Demiri, Miriam Abdo, Athanasios Tsianakas¹

¹Fachklinik Bad Bentheim, Am Bade 1, 48455, Bad Bentheim, Deutschland. a.tsianakas@fk-bentheim.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|December 14, 2021

Summary

This case study details erythrodermic psoriasis vulgaris flare-ups following SARS-CoV-2 infection. It highlights a COVID-19 trigger without medication, offering new insights into psoriasis exacerbation factors.

Keywords:

Exacerbation IL-17 Psoriasis vulgaris SARS-CoV‑2 Trigger

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Area of Science:

Dermatology
Infectious Diseases
Immunology

Background:

Psoriasis vulgaris is a chronic inflammatory skin condition.
Exacerbations can be triggered by infections and certain medications.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been anecdotally linked to psoriasis flares.

Observation:

A patient presented with acutely exacerbated erythrodermic psoriasis vulgaris.
The exacerbation occurred after symptomatic infection with SARS-CoV-2 (coronavirus disease 2019).
No obvious drug trigger was identified for this psoriasis flare.

Findings:

This case represents the first reported instance of erythrodermic psoriasis triggered by COVID-19 without a concurrent drug trigger.
It adds to the understanding of SARS-CoV-2 as a potential direct trigger for severe psoriasis.
The findings suggest a direct link between SARS-CoV-2 infection and psoriasis exacerbation.

Implications:

Highlights the need to consider viral infections, including SARS-CoV-2, as potential triggers for psoriasis.
May inform clinical management of psoriasis patients during viral pandemics.
Further research is warranted to elucidate the mechanisms linking SARS-CoV-2 and psoriasis pathogenesis.