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Peripheral Artery Disease: A Comprehensive Updated Review

Garba Rimamskep Shamaki1, Favour Markson2, Demilade Soji-Ayoade3

  • 1Department of Internal Medicine Unity Hospital/Rochester Regional Health Rochester, NY.

Current Problems in Cardiology
|December 15, 2021
PubMed

Insights

Peripheral arterial disease (PAD) affects over 200 million globally, leading to amputations and increased mortality. This review covers PAD

Area of Science:

  • Vascular Medicine
  • Cardiovascular Disease
  • Public Health

Background:

  • Peripheral arterial disease (PAD) impacts over 200 million worldwide, contributing to amputations and significant mortality.
  • PAD is a marker for systemic atherosclerosis, elevating risks of stroke, myocardial infarction, and cardiovascular death.
  • Despite advances in treatment, PAD prevalence remains high.

Purpose of the Study:

  • To provide current information on the clinical course of PAD.
  • To detail diagnostic methods for PAD.
  • To review medical and interventional management strategies for PAD.

Main Methods:

  • Literature review of clinical studies and guidelines on PAD.
  • Analysis of epidemiological data on PAD prevalence and outcomes.
  • Synthesis of information on conservative, pharmacological, and revascularization treatments for PAD.

Main Results:

  • PAD affects over 200 million globally, with significant amputation rates and mortality.
  • Interventional procedures like angioplasty with stents improve outcomes over medical therapy alone.
  • PAD indicates broader atherosclerotic disease, increasing risks for major adverse cardiovascular events.

Conclusions:

  • Early diagnosis and comprehensive management are crucial for PAD patients.
  • Percutaneous transluminal angioplasty offers improved outcomes for PAD.
  • Further research and public health initiatives are needed to address the high prevalence and impact of PAD.

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