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Related Concept Videos

Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

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Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
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Author Spotlight: Enhancing Microinjection Needle Quality by Wet Beveling
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Needle tip deformation in local dental anesthesia - A technical note.

Amely Hartmann1, Tina Lawall2, Luhrenberg Philipp1

  • 1Department of Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Augustusplatz 2, 55131, Mainz, Germany.

Journal of the Mechanical Behavior of Biomedical Materials
|December 15, 2021
PubMed
Summary

Dental local anesthesia cannula deformation was assessed using a novel animal model. Thinner 27-gauge cannulas showed less bending, but larger inner diameters and manufacturing defects increased deformation risks.

Keywords:
Bevel designCannulaCannula materialsCutting profileDeformationInner diameterLocal anesthesia

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Area of Science:

  • Dental materials science
  • Biomechanical engineering
  • Anesthesiology

Background:

  • Dental local anesthesia relies on cannulas for effective delivery.
  • Cannula integrity is crucial for safe and predictable anesthesia.
  • Understanding deformation factors can prevent complications.

Purpose of the Study:

  • To evaluate the mechanical deformation rate of dental cannula tips.
  • To simulate injection forces using a new animal model.
  • To compare deformation across different cannula gauges and types.

Main Methods:

  • An in vitro study utilizing a novel mechanical device for injection simulation.
  • Application of defined forces (100g for 60s) to pig jaw bone models.
  • Evaluation of 25-gauge and 27-gauge cannulas from local anesthesia syringes under digital microscopy.

Main Results:

  • 27-gauge cannulas exhibited a significantly lower likelihood of bending.
  • Cannulas with larger inner diameters showed higher deformation rates.
  • 12-38% of evaluated cannulas presented manufacturing defects and deformation.

Conclusions:

  • Cannula deformation is influenced by inner diameter, bevel, and cutting profile.
  • Repeated use may increase deformation, raising complication risks.
  • Material properties and manufacturing quality are critical for cannula integrity.