Related Experiment Video
Updated: Oct 10, 2025
03:53
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
1.4K
Gout and the COVID-19 pandemic
Vicky Tai1, Philip C Robinson2,3, Nicola Dalbeth1
1Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Current Opinion in Rheumatology
|December 15, 2021
Summary
People with gout face higher risks from COVID-19 due to existing conditions and inflammation. Gout treatments like colchicine show potential for COVID-19, but the pandemic negatively impacted gout care.
Area of Science:
- Rheumatology and Infectious Diseases
- Immunology and Inflammation
Background:
- Gout patients may experience worse COVID-19 outcomes due to cardiometabolic comorbidities.
- Chronic hyperuricemia and gout-induced inflammation can influence COVID-19 severity.
- Glucocorticoid use for gout flares might negatively affect COVID-19 outcomes and vaccine response.
Purpose of the Study:
- To review recent literature on COVID-19 and its impact on gout patients.
- To explore the relationship between gout pathophysiology and severe COVID-19.
- To assess the pandemic's effect on gout management and patient quality of life.
Main Methods:
- Systematic review of recently published articles.
- Analysis of clinical trial data on gout medications in COVID-19 treatment.
- Synthesis of findings on patient-reported outcomes and healthcare access.
Main Results:
- Gout patients are at increased risk for adverse COVID-19 outcomes.
- Gout medications like colchicine and IL-1 inhibitors show therapeutic potential for COVID-19.
- The pandemic has led to difficulties in gout disease control, medication access, and reduced quality of life for patients.
Conclusions:
- COVID-19 poses significant challenges for individuals with gout.
- Further research is needed to establish clear management guidelines for gout during pandemics.
- Understanding the interplay between gout and COVID-19 is crucial for patient care and treatment strategies.
More Related Videos
06:29Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
2.5K
06:35An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
7.3K
Related Concept Videos
01:11Genome-wide Association Studies-GWAS
14.7K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
14.7K
01:17Gastritis-II: Pathophysiology
679
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
679
01:26Factors Affecting the Risk of Infection
12.7K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.7K
01:05Single Nucleotide Polymorphisms-SNPs
16.7K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
16.7K
01:19Overview of Carbohydrate Metabolism
2.1K
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
2.1K
01:23Gastritis III: Clinical Manifestations and Management
575
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
575