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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

916
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
916
Pain01:20

Pain

726
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
726
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

521
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
521

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Related Experiment Video

Updated: Oct 10, 2025

A Preterm Rat Model for Pain Studies
01:37

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Published on: February 9, 2024

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Pain in Preterm Infants: Different Perspectives.

Hala Mahmoud Obeidat, Doa'a Abdullah Dwairej, Abdelkarim Saleh Aloweidi

    The Journal of Perinatal Education
    |December 15, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Neonates, especially preterm infants, experience pain, contrary to past beliefs. Effective non-pharmacological methods like nonnutritive sucking and skin-to-skin contact are now used to manage infant pain.

    Keywords:
    facilitated tuckingnonnutritive suckingpreterm infants painskin-to-skin contact

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    Area of Science:

    • Neonatal care
    • Pain management
    • Developmental pediatrics

    Background:

    • Historical misconceptions regarding neonatal pain perception have been debunked.
    • Neuroimaging confirms peripheral nervous system maturity by 24 weeks gestation.
    • Neonates and preterm infants possess lower pain thresholds, necessitating effective pain management.

    Purpose of the Study:

    • To review the evolution of neonatal pain management strategies.
    • To highlight the importance of addressing neonatal pain effectively.
    • To discuss the efficacy of various pharmacological and non-pharmacological interventions.

    Main Methods:

    • Literature review on neonatal pain management.
    • Analysis of studies investigating pain reduction strategies.
    • Synthesis of evidence on pharmacological and non-pharmacological interventions.

    Main Results:

    • Significant advancements in understanding and managing neonatal pain.
    • Established efficacy of non-pharmacological interventions.
    • Identified specific effective methods including nonnutritive sucking, skin-to-skin contact, and facilitated tucking.

    Conclusions:

    • Neonatal pain is a significant concern, particularly in preterm infants.
    • Non-pharmacological methods are effective and safe for neonatal pain control.
    • Continued research and implementation of evidence-based practices are crucial for optimal neonatal care.