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Updated: Oct 10, 2025
05:16
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
293
Mortality and Readmission Rates After Heart Failure: A Systematic Review and Meta-Analysis
Tian Lan1,2, Yan-Hui Liao3, Jian Zhang2
1Department of Health Care Management and Medical Education, The School of Military Preventive Medicine, Air Force Medical University, Xi'an, People's Republic of China.
Therapeutics and Clinical Risk Management
|December 15, 2021
Summary
Heart failure hospitalizations lead to significant 30-day and 1-year readmission and mortality rates. Risk factors for these outcomes require further investigation to improve patient care.
Area of Science:
- Cardiology
- Public Health
- Clinical Research
Background:
- Heart failure (HF) is a major cause of hospitalization.
- High readmission and mortality rates post-hospitalization indicate significant challenges in HF management.
Purpose of the Study:
- To systematically examine the rates of mortality and readmission after heart failure hospitalization.
- To identify key risk factors associated with these adverse outcomes.
Main Methods:
- A comprehensive systematic literature search was conducted across PubMed, Cochrane Library, and EMBASE.
- A meta-analysis using a random-effects model was performed on data from 27 studies involving 515,238 participants.
Main Results:
- The pooled 30-day all-cause readmission rate was 19% (95% CI 0.14-0.23) and 1-year rate was 53% (95% CI 0.46-0.59).
- All-cause mortality rates were 14% (95% CI 0.10-0.18) at 30 days and 29% (95% CI 0.25-0.33) at 1 year.
- Comorbidities were frequently observed in patients with heart failure.
Conclusions:
- Hospitalization for heart failure is associated with substantial 30-day and 1-year readmission and mortality.
- Understanding prevalent comorbidities is crucial for addressing these high rates.
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