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Updated: Oct 10, 2025

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Management of patients with allergy to local anesthetics: two case reports
Varun Arya1, Geetanjali Arora1, Sanjeev Kumar1
1Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, SGT University, Gurugram, India.
Abstract:
Lidocaine is the most commonly used local anesthetic (LA) agent in various dental as well as oral and maxillofacial procedures. Although rare, adverse effects and allergic reactions to lidocaine have been reported. In patients with suspected allergy to LA or a history of such reaction, careful history-taking and allergy testing should be performed to choose an alternative LA agent to avoid any adverse effects. Here, we present two cases of delayed hypersensitivity reaction to lidocaine, wherein the patients presented with erythema, edema, and itching. Intradermal testing confirmed allergic reaction to lidocaine, and the patients underwent successful dental treatment using an alternative LA agent. This report highlights the importance of allergy testing prior to LA use considering the serious consequences of allergy to these agents and describes the management of such patients using an alternative LA agent.
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