Evaluation of Potential Cumulative Risk of Multiple 1.5-T MRI Examinations in Patients With Cardiac Implanted
Saurabh Jha1, J Eric Schmitt1, Elena Motuzko2
1Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104.
Insights
Serial MRI scans in patients with cardiac implanted electronic devices (CIEDs) are safe. Multiple examinations did not increase the risk of adverse events, supporting current guidelines for using MRI in these patients.
Area of Science:
- Cardiovascular Imaging
- Medical Device Safety
- Radiology
Background:
- Professional societies endorse MRI for patients with non-conditional (legacy) cardiac implanted electronic devices (CIEDs).
- Concerns persist about cumulative adverse effects from repeated MRI examinations in patients with CIEDs.
Purpose of the Study:
- To evaluate the safety of serial 1.5-T MRI examinations in patients with CIEDs.
- To determine if the number of previous MRI scans impacts adverse event rates.
Main Methods:
- Retrospective analysis of 599 MRI examinations in 481 patients with CIEDs.
- Inclusion of patients undergoing multiple examinations (up to seven).
- Monitoring for major and minor adverse events.
Main Results:
- No major adverse events were reported across all examinations.
- The overall minor adverse event rate was 5.7%.
- Statistical analysis revealed no increased adverse event rate with a higher number of prior MRI examinations.
Conclusions:
- Serial 1.5-T MRI examinations are safe for patients with legacy CIEDs.
- The cumulative number of MRI scans does not elevate the risk of adverse events.
- Findings support the continued use of MRI in patients with CIEDs as per current guidelines.
Abstract:
Although professional societies now support MRI in patients with nonconditional (legacy) cardiac implanted electronic devices (CIEDs), concern remains regarding potential cumulative effects of serial examinations. We evaluated 481 patients with CIEDs who underwent 599 1.5-T MRI examinations (44.6% cardiac examinations), including 68 patients who underwent multiple examinations (maximum, seven examinations). No major events occurred. The minor adverse event rate was 5.7%. Multiple statistical evaluations showed no increase in adverse event rate with increasing number of previous examinations.
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