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Factors Associated with a Failed Nonoperative Reduction of Intussusception in Children
Bahubali Deepak Gadgade1, Veerabhadra Radhakrishna1, Nitin Kumar1
1Department of Paediatric Surgery, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Insights
Delayed presentation and abdominal distension are key factors in failed nonoperative reduction of intussusception in children. These indicators increase the risk of surgical intervention and potential intestinal nonviability.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Medical Diagnostics
Background:
- Intussusception is a common surgical emergency in infants and children.
- Nonoperative reduction is the primary treatment modality.
- Identifying factors for reduction failure is crucial for timely intervention.
Purpose of the Study:
- To evaluate factors associated with failed nonoperative reduction of intussusception.
- To identify predictors of increased need for surgery in intussusception cases.
Main Methods:
- Retrospective study including children diagnosed with intussusception.
- Analysis of data from a tertiary care pediatric surgery hospital (November 2013 - February 2020).
- Utilized pneumatic reduction and logistic regression analysis.
Main Results:
- 84% of 106 children had successful pneumatic reduction.
- Presentation at or after 48 hours and abdominal distension significantly increased failure risk (OR=11.3 and OR=4.46 respectively).
- Delayed presentation and abdominal distension also predicted increased need for surgery (OR=2.812 and OR=8.758 respectively).
Conclusions:
- Late presentation (≥48 hours) and abdominal distension are significant risk factors for failed nonoperative reduction.
- These factors are associated with a higher likelihood of requiring surgery.
- Delayed diagnosis increases the risk of intestinal nonviability.
Aims:
The aim of this study was to evaluate the factors associated with the failure of nonoperative reduction of intussusception in children.
Methods:
A retrospective study was conducted in a tertiary care pediatric surgery hospital. The children admitted to the department of pediatric surgery between November 2013 and February 2020 with the diagnosis of Intussusception were included.
Results:
A total of 106 (67%) children underwent pneumatic reduction. Eighty-nine (84%) children had a successful reduction. A higher rate of failed reduction was found in children who presented at or after 48 h of the onset of symptoms (P = 0.03) and abdominal distension at presentation (P < 0.002). On multiple logistic regression analysis, the children presenting at or after 48 h of the onset of symptoms (odds ratio [OR] = 11.3; P = 0.039) and abdominal distension at presentation (OR = 4.46; P = 0.021) were found to be associated with increased risk of failure of nonoperative reduction. The variables age <1 year, weight <10 kg, pain abdomen, vomiting, bilious vomiting, fever, bleeding per rectum, and palpable mass were not associated with the failed nonoperative reduction. The variables, presentation at or after 48 h of the onset of symptoms (OR = 2.812; P = 0.045) and abdominal distension at presentation (OR = 8.758; P = 0.000) were found to be associated with an increased need for surgery.
Conclusion:
The risk factors for failed nonoperative reduction of intussusception include a presentation at or after 48 h of the onset of symptoms and the presence of abdominal distension at presentation. The delayed presentation was associated with the increased need for surgery and increased chances of intestinal nonviability.
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