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[Neurotherapy of the hyperactive bladder].

K P Jünemann, P De Geeter, C Persson

    Der Urologe. Ausg. A
    |September 1, 1986
    PubMed
    Summary
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    Peripheral neurostimulation targeting the S2 dorsal root offers a promising treatment for overactive bladder. This neurotherapy normalized bladder function and significantly increased bladder capacity in patients.

    Area of Science:

    • Urology
    • Neuroscience
    • Anatomy

    Context:

    • Current treatments for non-neurogenic bladder hyperactivity yield unsatisfactory results.
    • Emerging evidence in lower urinary tract neuroanatomy and neurophysiology suggests new therapeutic avenues.
    • Peripheral neurostimulation presents a novel approach for managing bladder dysfunction.

    Purpose:

    • To investigate the efficacy of peripheral neurostimulation of the S2 dorsal root or dorsal nerve of the penis for treating hyperactive bladder dysfunction.
    • To evaluate the impact of S2-dorsal root blockade with local anesthesia on bladder hyperactivity.
    • To report initial findings from a cohort of patients undergoing this novel neurotherapy.

    Summary:

    • Peripheral neurostimulation and S2-dorsal root blockade were applied to 14 patients with bladder hyperactivity.

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  • Neurotherapy resulted in normalized bladder function and up to a 400% increase in bladder capacity.
  • The study discusses the methods, outcomes, and potential complications of this treatment approach.

    • Impact:

    • This study introduces a potentially effective treatment for hyperactive bladder, addressing limitations of current therapies.
    • Peripheral neurostimulation offers a new therapeutic strategy for patients with refractory bladder hyperactivity.
    • Findings may guide future research and clinical application of neurostimulation for lower urinary tract symptoms.