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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
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Melanoma: An update on systemic therapies.
Lauren Skudalski1, Reid Waldman1, Philip E Kerr1
1Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut.
Journal of the American Academy of Dermatology
|December 16, 2021
Summary
Melanoma remains a significant cause of skin cancer death. This article reviews systemic and local treatments for unresectable, metastatic, or recurrent melanoma, offering dermatologists current knowledge on oncologist-prescribed therapies.
Area of Science:
- Dermatology
- Oncology
- Cancer Research
Background:
- Melanoma is a major cause of skin cancer mortality despite early detection advances.
- Surgical removal is not feasible for patients with unresectable or metastatic melanoma.
- Systemic and local therapies are crucial for managing advanced melanoma.
Purpose of the Study:
- To provide dermatologists with current knowledge on melanoma treatment options.
- To detail therapies prescribed by oncologists for advanced melanoma.
- To cover unresectable stage III, stage IV, and recurrent melanoma.
Main Methods:
- Review of current systemic and local treatment options for melanoma.
- Focus on therapies prescribed by oncologists.
- Information targeted towards dermatologists.
Main Results:
- N/A - This is a review article, not a study with primary results.
- Provides an overview of available treatment modalities.
Conclusions:
- Dermatologists require up-to-date knowledge of advanced melanoma treatments.
- Collaboration with oncologists is key for managing complex melanoma cases.
- Systemic and local therapies are essential when surgery is not an option.
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