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Time Since Lower-Limb Amputation: An Important Consideration in Mobility Outcomes.

Mayank Seth¹, Emma Haldane Beisheim, Ryan Todd Pohlig

¹From the Delaware Limb Loss Studies, University of Delaware, Department of Physical Therapy (MS, EHB, JMS); University of Delaware, Biostatistics Core Facility (RTP); Independence Prosthetics-Orthotics, Inc (JRH); and Christiana Spine Center, Newark, Delaware (FBS).

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Summary

Time since amputation (TSAmp) impacts mobility outcomes in adults with lower-limb amputation. Longer TSAmp may correlate with better scores on some mobility tests, but associations vary for others.

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Area of Science:

Rehabilitation Medicine
Biomedical Engineering
Clinical Biomechanics

Background:

Mobility is crucial for community-dwelling adults post-lower-limb amputation.
Understanding factors influencing long-term mobility outcomes is essential for effective rehabilitation.

Purpose of the Study:

To investigate the association between time since amputation (TSAmp) and various mobility outcomes in adults with lower-limb amputation.
To determine if TSAmp influences performance on standardized mobility assessments.

Main Methods:

Secondary analysis of a cross-sectional dataset of 109 adults with unilateral transfemoral or transtibial amputation.
Utilized mobility outcome measures including the Prosthesis Evaluation Questionnaire-Mobility Subscale, timed up and go, 10-m walk test, and 6-min walk test.
Statistical analyses controlled for age, sex, amputation level, and etiology.

Main Results:

Time since amputation (TSAmp) showed significant associations with all tested mobility outcomes.
Linear associations were found between TSAmp and the Prosthesis Evaluation Questionnaire-Mobility Subscale (10.6% variance) and timed up and go test (8.4% variance).
Nonlinear associations were observed between TSAmp and the 10-m walk test (12.1% variance) and 6-min walk test (13.2% variance).

Conclusions:

Longer time since amputation may be linked to improved scores on the Prosthesis Evaluation Questionnaire-Mobility Subscale and better timed up and go test performance.
The relationship between TSAmp and 10-m walk test speed/6-min walk test distance can be complex, with potential for both improvement and decline.
Time since amputation is a critical factor to consider when estimating postamputation mobility in adults.