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Leukocyte chemotactic factor 2-related amyloidosis presenting with severe jaundice and hepatic encephalopathy
Hussam Almasri1, Almurtada Razok1, Ahmed Badi2
1Department of Medicine Hamad Medical Corporation Doha Qatar.
Abstract:
Amyloidosis is a well-known disease with various types and subtypes. One of the most recently identified types is leukocyte chemotactic factor 2 amyloidosis (LECT 2), which was found to be common in certain ethnic backgrounds. It is suggested that the diagnosis of this type is vital to prevent any therapy-related complications when it is erroneously diagnosed as AL amyloidosis. The clinical presentation is usually slowly progressive kidney disease and mild hepatic impairment. We report a case of LECT2 amyloidosis, which presented with severe painless cholestasis and hepatic encephalopathy alongside progressive kidney disease.
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