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Feasibility of cognitive rehabilitation in patients with advanced multiple sclerosis: A pilot study
Stefanos E Prouskas1, Nancy D Chiaravalloti2, Neeltje Kant3
1Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Anatomy & Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, The Netherlands.
Background:
The feasibility of cognitive rehabilitation is rarely investigated in patients with advanced multiple sclerosis.
Methods:
Eighteen patients with advanced multiple sclerosis (median EDSS = 7.5) were randomized into restorative or compensatory cognitive rehabilitation. Feasibility was determined by adherence rate, completion rate, patient satisfaction, self-reported fatigue, training difficulty, and training duration.
Results:
Adherence rates and completion rates were over 70%, and patients were highly satisfied in both groups. Energy levels decreased minimally during the sessions (pre = 6.9 vs post = 6.4). Training difficulty (4.6) and duration (5.7) were close to ideal (scale 1-10, 5 = ideal).
Conclusions:
Cognitive rehabilitation, with minor adjustments, appears feasible in patients with advanced multiple sclerosis.
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