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COVID-19 in Immunocompromised Patients: A Systematic Review
Anna Stainer1,2, Francesco Amati1,2, Giulia Suigo2
1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Seminars in Respiratory and Critical Care Medicine
|December 17, 2021
Summary
This systematic review examines COVID-19 in immunocompromised patients, detailing clinical features, disease severity, treatments, and vaccine responses in this vulnerable group.
Area of Science:
- Infectious Diseases
- Immunology
- Public Health
Background:
- Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes the ongoing global pandemic.
- Over 200 million infections and 4 million deaths worldwide have been reported.
- Limited data exists on COVID-19 outcomes in immunocompromised individuals.
Purpose of the Study:
- To systematically review clinical presentation, disease severity, and treatment of COVID-19 in immunocompromised patients.
- To assess the response to vaccination against SARS-CoV-2 in this population.
- To analyze data across different types and severities of immunosuppression.
Main Methods:
- Systematic literature review.
- Data extraction on clinical characteristics, severity, and treatment.
- Analysis of vaccination response in immunocompromised subgroups.
Main Results:
- (Results will be populated upon study completion)
- (Results will be populated upon study completion)
- (Results will be populated upon study completion)
Conclusions:
- (Conclusions will be populated upon study completion)
- (Conclusions will be populated upon study completion)
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