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Psychometric Validation of the CLEFT-Q Patient Reported Outcome Measure: A Prospective Study to Examine
Anna Miroshnychenko1, Charlene Rae1, Karen Wong Riff2
13710McMaster University, Hamilton, Canada.
Summary
The CLEFT-Q, a patient-reported outcome measure for cleft lip and/or palate, demonstrated strong construct validity. This study confirms the CLEFT-Q
Area of Science:
- Cleft lip and palate research
- Patient-reported outcome measures (PROMs)
- Psychometric validation
Background:
- Cleft lip and/or palate (CL/P) significantly impacts patients' lives.
- Patient-reported outcome measures (PROMs) are crucial for assessing treatment outcomes.
- The CLEFT-Q is a condition-specific PROM designed for CL/P patients.
Purpose of the Study:
- To evaluate the cross-sectional construct validity of the CLEFT-Q scales.
- To provide evidence for the psychometric properties of the CLEFT-Q instrument.
- To support the use of CLEFT-Q in clinical and research settings.
Main Methods:
- Prospective study design involving seven international cleft centers.
- Participants (n=177) aged 8-29 years with CL/P completed CLEFT-Q and other PROMs.
- Hypothesis testing of correlations between CLEFT-Q scales and related constructs using Spearman correlations.
Main Results:
- Overall, 73% of the tested hypotheses for construct validity were supported.
- Strong correlations were observed between CLEFT-Q appearance scales and related measures (77% supported).
- Significant support was found for correlations involving health-related quality of life scales (67-70% supported).
Conclusions:
- The CLEFT-Q demonstrates robust cross-sectional construct validity.
- These findings provide further evidence of the CLEFT-Q's psychometric reliability and utility.
- The CLEFT-Q is a validated instrument for assessing outcomes in patients with cleft lip and/or palate.
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