Outcomes after reperfusion therapies in patients with ACA stroke: A multicenter cohort study from the EVATRISP

A Filioglo1, N Simaan1, A Honig1

  • 1Departments of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Insights

For anterior cerebral artery strokes, endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) show similar safety and effectiveness. Treatment outcomes were not affected by clot location within the anterior cerebral artery (ACA).

Area of Science:

  • Neurology
  • Vascular Neurology
  • Interventional Neurology

Background:

  • Anterior cerebral artery (ACA) strokes often lead to poor patient outcomes.
  • The optimal acute treatment for ACA occlusive strokes remains uncertain.

Purpose of the Study:

  • To compare the effectiveness and safety of endovascular thrombectomy (EVT) versus intravenous thrombolysis (IVT) for acute anterior cerebral artery (ACA) strokes.

Main Methods:

  • Retrospective analysis of 92 patients with isolated ACA stroke from the EVATRISP registry.
  • Comparison of outcomes between patients treated with EVT and those treated with IVT using multivariate regression analysis.

Main Results:

  • No significant differences in favorable outcome, mortality, or symptomatic intracranial hemorrhage between EVT and IVT groups.
  • EVT patients more frequently presented with wake-up strokes and proximal occlusions.
  • Clot location within the ACA (A1 vs. A2/A3 segments) did not influence treatment outcomes.

Conclusions:

  • Both IVT and EVT appear to be safe and similarly effective treatments for ACA strokes.
  • Treatment efficacy for ACA strokes may be independent of the specific clot location within the artery.
Abstract

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