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Exfoliation syndrome.

A H Tarkkanen

    Transactions of the Ophthalmological Societies of the United Kingdom
    |January 1, 1986
    PubMed
    Summary

    Exfoliation syndrome affects diverse global populations and varies by age and sex. Early recognition is crucial for managing intraocular pressure and surgical complications.

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    Area of Science:

    • Ophthalmology
    • Genetics
    • Epidemiology

    Background:

    • Exfoliation syndrome is a global condition affecting various ethnic groups.
    • Prevalence varies significantly with age, ethnicity, and sex, with higher rates in females and earlier onset in Bantu populations.
    • Familial occurrence suggests a potential genetic link, possibly autosomal dominant.

    Purpose of the Study:

    • To summarize the global prevalence and demographic variations of exfoliation syndrome.
    • To highlight the clinical significance of exfoliation syndrome in patient management and surgical outcomes.
    • To emphasize the need for further population-based studies to understand prevalence differences.

    Main Methods:

    • Review of existing population-based surveys and genetic studies on exfoliation syndrome.
    • Analysis of prevalence data across different age groups, ethnicities, and sexes.
    • Clinical observation of complications and surgical considerations in exfoliation patients.

    Main Results:

    • Exfoliation syndrome prevalence increases with age, particularly after 60 in Caucasians, but shows earlier onset in Bantu populations.
    • Females exhibit a higher prevalence than males in population-corrected surveys.
    • 20% of patients present with intraocular pressure abnormalities, and 2% experience lens displacement, complicating cataract surgery.

    Conclusions:

    • Exfoliation syndrome requires global recognition due to its widespread occurrence and clinical impact.
    • Age and ethnicity are critical factors influencing prevalence, necessitating further research.
    • Clinical vigilance is essential for managing associated risks, including elevated intraocular pressure and surgical challenges.

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