Bos taurus haplotypes segregating in Nellore (Bos indicus) cattle
Y T Utsunomiya1,2,3, A A A D Fortunato1,2,4, M Milanesi3,5
1Department of Production and Animal Health, School of Veterinary Medicine of Araçatuba, São Paulo State University, 16050-680 R. Clovis Pestana 793 - Dona Amelia, Araçatuba, SP, Brazil.
Animal Genetics
|December 18, 2021
Summary
Brazilian Nellore cattle, despite being Bos indicus, possess taurine (Bos taurus) ancestry. This study identified taurine haplotypes influencing economically important traits, offering new targets for genetic improvement in beef cattle.
Area of Science:
- Animal Genetics
- Genomics
- Livestock Breeding
Background:
- Brazilian Nellore cattle (Bos indicus) have a complex ancestry involving Bos taurus lineage.
- This taurine introgression, though small on average, carries significant genetic variants impacting traits.
Purpose of the Study:
- To identify and characterize taurine haplotypes in Brazilian Nellore cattle.
- To investigate the association of these haplotypes with economically important traits.
Main Methods:
- Genotyping of 9074 Nellore animals using 539,657 imputed SNP markers.
- Analysis of taurine haplotypes and their association with 22 economically important traits and previously reported QTL.
Main Results:
- Identified common taurine haplotypes (>3%) beyond known variants like PLAG1-Q and Guarani polled (PG).
- These haplotypes are associated with genes related to immunity, growth, reproduction, and hair/skin phenotypes.
- Many major quantitative trait loci (QTL) in Nellore cattle are partially driven by these taurine haplotypes.
Conclusions:
- Taurine haplotypes play a significant role in the genetic makeup and trait variation of Brazilian Nellore cattle.
- These findings provide valuable genetic targets for future breeding strategies and genetic improvement programs in Nellore cattle.
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