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Updated: Oct 9, 2025

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Published on: September 15, 2023
Synchronous Parathyroidectomy and Extended Thymectomy in Multiple Endocrine Neoplasia Type 1
Dean P Robinson1, Alexander E P Smith2, Andrea Bille2
1Guy's King's and St Thomas' School of Medical Education, London, United Kingdom.
Abstract:
A 49-year-old man presented with symptoms of hypercalcemia that had been present for 3 months. An initial chest x-ray showed a large anterior mediastinal mass. Subsequent computed tomography also demonstrated a calcified lesion in the uncinate process of the pancreas, and a neck ultrasound showed parathyroid lesions. The combination of symptoms and tumors raised the possibility of multiple endocrine neoplasia type 1 as the diagnosis. The lesions were later biopsy-proven to be atypical carcinoid neuroendocrine tumors. The patient underwent simultaneous neck dissection for bilateral subtotal parathyroidectomy and midline sternotomy for thymectomy of the large mediastinal mass.

