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Staphylococcus lugdunensis as Cause of Septic Pericarditis

Suha Abu Khalaf1, Abdallah Mansour2, Isma Perveze3

  • 1Department of Internal Medicine, Division of Infectious Diseases, University of Missouri-Columbia, Columbia, Missouri (UMC COMO).

Missouri Medicine
|December 20, 2021
PubMed

Insights

Staphylococcus lugdunensis, a skin bacterium, can cause severe infections like endocarditis. This case highlights its potential to cause pericarditis, sepsis, and DIC, emphasizing its pathogenic significance.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Staphylococcus lugdunensis (S. lugdunensis) is a coagulase-negative staphylococcus found on skin.
  • It shares virulence factors like biofilm formation with Staphylococcus aureus (S. aureus).
  • S. lugdunensis is linked to severe infections including endocarditis, bacteremia, and foreign body infections.

Observation:

  • This report details a rare case of pericarditis secondary to S. lugdunensis.
  • The patient, a 69-year-old woman, presented with sepsis and disseminated intravascular coagulopathy (DIC).

Findings:

  • S. lugdunensis was identified as the causative agent of pericarditis, sepsis, and DIC in this patient.
  • This represents the first reported case of pericarditis caused by S. lugdunensis.

Implications:

  • The findings suggest S. lugdunensis should be considered a significant pathogen, not a contaminant, in severe infections.
  • This case expands the spectrum of known S. lugdunensis-associated diseases.
  • Further research is needed to understand the pathogenesis and optimal treatment of S. lugdunensis-induced pericarditis.

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