Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

436
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
436
Association Areas of the Cortex01:21

Association Areas of the Cortex

6.8K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.8K
Prosopagnosia01:24

Prosopagnosia

370
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
370
Lateralization01:28

Lateralization

624
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
624
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

5.1K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
5.1K
Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

1.8K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Rather Than Vertical-Selective Saccadic Abnormalities in Progressive Supranuclear Palsy.

Annals of clinical and translational neurology·2026
Same author

Multidimensional Safety Assessment of a Low-Intensity Scanning Ultrasound (SUS) Protocol in Sheep.

Ultrasound in medicine & biology·2026
Same author

Early Simultaneous Brain Indexes of Phonological, Semantic, and Pragmatic Information Access in Language Understanding and Production.

Journal of cognitive neuroscience·2026
Same author

Where do we predict communicative function? New arguments for the relevance of sensorimotor brain areas in language understanding.

Neuropsychologia·2026
Same author

Differentiating Behavioural Presentations of Biomarker-Confirmed Alzheimer's Disease from Frontotemporal Lobar Degeneration Using the Addenbrooke's Cognitive Examination-III.

Dementia and geriatric cognitive disorders·2026
Same author

How language modulates color perception in a brain-constrained deep neural network.

iScience·2026

Related Experiment Video

Updated: Oct 9, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K

What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy.

Zubaida Shebani1,2, Peter J Nestor3, Friedemann Pulvermüller1,4,5,6

  • 1Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom.

Frontiers in Human Neuroscience
|December 20, 2021
PubMed
Summary

Patients with Posterior Cortical Atrophy (PCA) show impaired working memory for spatial prepositions. This suggests posterior brain regions are crucial for processing words with spatial meaning.

Keywords:
PCAcategory specific impairmentsembodiment cognitionposterior cortical atrophysemantic processingspatial language processingspatial prepositionsworking memory

More Related Videos

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection
07:04

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection

Published on: March 10, 2021

4.2K
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

6.9K

Related Experiment Videos

Last Updated: Oct 9, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection
07:04

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection

Published on: March 10, 2021

4.2K
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

6.9K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Linguistics

Background:

  • Posterior cortical atrophy (PCA) affects brain regions vital for visuo-spatial processing.
  • Understanding PCA's impact on language is key to semantic theories.

Purpose of the Study:

  • To determine if posterior brain lesions functionally impact processing of spatial language.
  • To investigate working memory deficits for spatial prepositions in PCA patients.

Main Methods:

  • A case series comparing PCA patients with matched healthy controls.
  • Assessed immediate and delayed serial recall for number words, spatial prepositions, and function words.
  • Controlled for psycholinguistic and semantic variables across word categories.

Main Results:

  • PCA patients exhibited significantly impaired delayed recall of spatial prepositions compared to controls.
  • No significant differences were observed for number words or function words.

Conclusions:

  • Lesions in posterior parieto-occipital regions specifically impair spatial preposition processing.
  • Posterior cortical regions play a vital role in the semantic processing of spatial language.
  • Findings support modality-specific semantic theories linking sensorimotor regions to conceptual processing.