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Updated: Oct 9, 2025

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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Early mobilization in acute stroke phase: a systematic review
Jéssica Mariana de Aquino Miranda1, Viviany Mendes Borges2, Rodrigo Bazan3
1Master student in Physical Therapy, Federal University of Triângulo Mineiro, Uberaba Minas Gerais Brazil.
Topics in Stroke Rehabilitation
|December 20, 2021
Summary
Early mobilization, involving out-of-bed activities, improves functional capacity and reduces complications in acute stroke patients. Optimal timing is after 24 hours, with sessions of 15-45 minutes focusing on sitting, standing, and walking.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Clinical Research
Background:
- Early mobilization, defined as out-of-bed activities during the acute stroke phase, is recognized for enhancing functional capacity and mitigating post-stroke complications.
- This systematic review focuses on the critical role of early mobilization in the acute phase of stroke recovery.
Approach:
- A systematic review was conducted, searching major databases for clinical trials on stroke and early mobilization.
- Studies published up to June 2020 involving acute stroke patients were included.
- Risk of bias and evidence levels were assessed, with safety evaluated via adverse effects.
Key Points:
- Seven studies with 8663 patients were synthesized, focusing on activities like sitting, standing, and walking.
- Early mobilization demonstrated improvements in functional capacity, as measured by the modified Rankin Scale score at 3 months.
Conclusions:
- Early mobilization in acute stroke patients is recommended to commence after 24 hours, contingent on hemodynamic stability and safety.
- Recommended mobilization duration is 15-45 minutes, performed one to three times daily, emphasizing sitting, standing, and walking.
- Early mobilization is a safe and effective strategy for improving functional outcomes in acute stroke survivors.

