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The Total Nutrient Index is a Useful Measure for Assessing Total Micronutrient Exposures Among US Adults
Alexandra E Cowan1, Regan L Bailey1, Shinyoung Jun1
1Department of Nutrition Science, Purdue University, West Lafayette, IN, USA.
The Journal of Nutrition
|December 20, 2021
Summary
The Total Nutrient Index (TNI) effectively assesses total micronutrient intake, including dietary supplements, for US adults. This nutrient-based approach offers a more comprehensive exposure assessment than traditional dietary indices.
Area of Science:
- Nutrition Science
- Dietary Assessment
- Public Health
Background:
- Traditional dietary indices often exclude dietary supplements (DS), overlooking substantial micronutrient contributions.
- A comprehensive nutrient-based approach is needed to accurately assess total micronutrient exposure.
Purpose of the Study:
- To examine the construct and criterion validity of the Total Nutrient Index (TNI) in US adults.
- To assess the TNI's ability to capture total micronutrient intake from both foods and DS.
Main Methods:
- The TNI was developed using 8 underconsumed micronutrients (calcium, magnesium, potassium, choline, vitamins A, C, D, E).
- Data from exemplary menus and NHANES surveys (2003-2014) were used for validation.
- TNI scores were correlated with the Healthy Eating Index (HEI)-2015 and biomarker data.
Main Results:
- The TNI demonstrated high scores on exemplary menus (84.8-93.3/100) and moderate correlation with HEI-2015 (r=0.48).
- TNI scores were significantly higher for DS users, nonsmokers, and food-secure individuals.
- TNI vitamin component correlations with biomarkers were higher than diet-alone correlations.
Conclusions:
- The Total Nutrient Index (TNI) is a valid and useful tool for assessing total micronutrient exposure in US adults.
- The TNI provides a more complete picture of nutrient intake by incorporating dietary supplements.

