Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

76.0K
Overview
76.0K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

15.1K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
15.1K
Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

6.2K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
6.2K
Transgenic Organisms00:53

Transgenic Organisms

31.8K
Overview
31.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Commentary on "Pandemics and Beyond: Considerations When Personal Risk and Professional Obligations Converge".

The Journal of clinical ethics·2021
Same author

Micro and Macro Ethical Considerations of COVID-19.

The Journal of clinical ethics·2020
Same author

On a communitarian approach to bioethics.

Theoretical medicine and bioethics·2011
Same author

Authoritarian versus responsive communitarian bioethics.

Journal of medical ethics·2010
Same author

A communitarian approach: a viewpoint on the study of the legal, ethical and policy considerations raised by DNA tests and databases.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2006
Same author

Bookmarks for public sociologists.

The British journal of sociology·2005
Same journal

What Should Be Our Utmost Goals in Teaching Medical Students Ethics.

The Journal of clinical ethics·2026
Same journal

How Should Physicians Interpret Legislatures' Lists of Exceptions to Abortion Restrictions?

The Journal of clinical ethics·2026
Same journal

ECMO Used for the Benefit of a Patient's Family: Case Study.

The Journal of clinical ethics·2026
Same journal

How Should Pregnancy-Related Morbidity and Mortality in Abortion-Restricted States Be Documented, Collected, and Reported After <i>Dobbs</i>?

The Journal of clinical ethics·2026
Same journal

The Latest Data on Medical Aid in Dying in the United States and What It Tells Us.

The Journal of clinical ethics·2026
Same journal

How Should Researchers Study Abortion Care Later in Pregnancy After <i>Dobbs</i>?

The Journal of clinical ethics·2026
See all related articles

Related Experiment Video

Updated: Oct 9, 2025

Generation of Genetically Modified Mice through the Microinjection of Oocytes
10:19

Generation of Genetically Modified Mice through the Microinjection of Oocytes

Published on: June 15, 2017

21.0K

For Faster Science: Accelerated Genetic Engineering.

Amitai Etzioni1

  • 1University Professor and Professor of International Relations at George Washington University in Washington, District of Columbia USA. icps@gwu.edu.

The Journal of Clinical Ethics
|December 20, 2021
PubMed
Summary
This summary is machine-generated.

Delaying genetic engineering research incurs significant human costs, despite acknowledged risks. Advancing genetic technologies offers potential to prevent premature deaths and alleviate suffering from genetic conditions.

More Related Videos

Mouse Genome Engineering Using Designer Nucleases
12:04

Mouse Genome Engineering Using Designer Nucleases

Published on: April 2, 2014

29.0K
Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus
11:36

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus

Published on: November 20, 2016

9.9K

Related Experiment Videos

Last Updated: Oct 9, 2025

Generation of Genetically Modified Mice through the Microinjection of Oocytes
10:19

Generation of Genetically Modified Mice through the Microinjection of Oocytes

Published on: June 15, 2017

21.0K
Mouse Genome Engineering Using Designer Nucleases
12:04

Mouse Genome Engineering Using Designer Nucleases

Published on: April 2, 2014

29.0K
Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus
11:36

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus

Published on: November 20, 2016

9.9K

Area of Science:

  • Biotechnology
  • Medical Ethics
  • Genetics

Background:

  • Societal debate on genetic engineering has spanned decades.
  • Public opinion has largely shifted to support genetic interventions.
  • Ethical considerations and potential risks are acknowledged.

Purpose of the Study:

  • To assert that delaying genetic engineering research has high human costs.
  • To highlight the potential benefits of genetic engineering in preventing disease and suffering.
  • To argue for continued advancement in genetic technologies.

Main Methods:

  • This article presents a qualitative analysis of the ethical and societal implications of genetic engineering.
  • It synthesizes arguments regarding the benefits of genetic interventions versus the costs of delay.
  • No specific experimental methods are detailed; it is a discourse-based review.

Main Results:

  • Delaying genetic engineering research leads to preventable suffering and premature deaths.
  • Genetic engineering holds the potential to significantly reduce the burden of genetic diseases.
  • Societal support for genetic interventions is growing, indicating readiness for advancement.

Conclusions:

  • The human cost of delaying genetic engineering research outweighs the perceived risks.
  • Advancements in genetic technology should be pursued to address critical health challenges.
  • Social justice concerns can be reconciled with scientific progress in genetic engineering.