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Cleaning the brain through turbulent glymphatic flow: The washing machine hypothesis
1Departments of Medical Imaging, Medicine, and Biomedical Engineering, University of Arizona, Tucson, Arizona, USA.
Lymphology
|December 20, 2021
Abstract:
In a thought experiment, a "washing machine" model is proposed based on turbulent flow from complex multi-dimensional forces to characterize fluid dynamics in the brain. The glymphatic system's hypothetical role in this system is illustrated in a series of diagrams. Implications of this model are discussed in terms of normal physiology and a variety of pathologic conditions such as brain atrophy and Alzheimer disease.
