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Related Experiment Video

Updated: Oct 9, 2025

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New concept for colonoscopy including side optics and artificial intelligence.

Joel Troya1, Adrian Krenzer2, Krzysztof Flisikowski3

  • 1Interventional and Experimental Endoscopy (InExEn), Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

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Summary

Combining artificial intelligence (AI) with side optics in a new colonoscopy prototype improves adenoma detection during colorectal cancer screening, identifying lesions missed by conventional methods.

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Area of Science:

  • Gastroenterology
  • Medical Technology
  • Artificial Intelligence

Background:

  • Adenoma detection rate is critical for effective colorectal cancer screening.
  • Side optics enhance visualization of flat adenomas obscured by folds.
  • Artificial intelligence (AI) shows promise in improving adenoma detection.

Purpose of the Study:

  • To develop and evaluate a novel colonoscopy concept combining side optics and AI.
  • To assess the efficacy of this combined technology in detecting adenomas.

Main Methods:

  • A 3D-printed cap with microcameras was integrated into a conventional endoscope.
  • An AI system was trained using images from the microcameras in gene-targeted pigs.
  • The prototype's adenoma detection capabilities were tested in a preclinical setting.

Main Results:

  • The prototype successfully detected adenomas that could be missed with conventional colonoscopy.
  • The AI system effectively identified and marked adenomas visualized by the side optics, including those outside the standard field of view.

Conclusions:

  • The integration of AI with side optics presents a promising advancement in colonoscopy technology.
  • This combined approach has the potential to significantly improve adenoma detection rates, thereby enhancing colorectal cancer screening efficacy.