Six-month follow-up of functional status in discharged patients with coronavirus disease 2019

Hou-Wei Du1,2, Shuang-Fang Fang1,2, Sang-Ru Wu1,2

  • 1Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Gulou District, Fuzhou, 35000, China.

BMC Infectious Diseases
|December 21, 2021
PubMed

Insights

A significant portion of COVID-19 survivors experience incomplete functional recovery six months post-discharge. Muscle or joint pain at onset is linked to a higher risk of long-term disability in these patients.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Rehabilitation Medicine

Background:

  • The long-term functional outcomes for patients recovering from COVID-19 are not well-established.
  • Understanding post-discharge functional status is crucial for patient recovery and healthcare planning.

Purpose of the Study:

  • To evaluate the 6-month functional status of COVID-19 survivors after hospital discharge.
  • To identify risk factors associated with incomplete functional recovery in these patients.

Main Methods:

  • A retrospective observational study was conducted on 95 COVID-19 survivors admitted to Union Hospital, Wuhan, China.
  • Functional outcomes were assessed using the Post-COVID-19 Functional Status (PCFS) scale at 6-month follow-up.
  • Logistic regression analysis identified risk factors for incomplete functional status (PCFS > 0).

Main Results:

  • At 6 months, 70.5% of patients achieved complete functional recovery (PCFS grade 0).
  • 12.6% experienced mild, and 7.4% moderate functional limitations.
  • Onset symptoms of muscle or joint pain were significantly associated with an increased risk of incomplete function (adjusted OR 3.39).

Conclusions:

  • A notable proportion of COVID-19 survivors face incomplete functional recovery six months post-discharge.
  • Early symptoms like muscle/joint pain may predict poorer long-term functional outcomes.
  • Targeted intervention strategies are necessary to address the functional deficits in COVID-19 survivors.
Abstract