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Can Generative Adversarial Networks help to overcome the limited data problem in segmentation?

Gerd Heilemann1, Mark Matthewman2, Peter Kuess1

  • 1Department of Radiation Oncology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Zeitschrift Fur Medizinische Physik
|December 21, 2021
PubMed
Summary

Generative Adversarial Networks (GANs) did not outperform U-Net for medical image segmentation tasks with small datasets. Performance significantly improved with increased training data size for both models.

Keywords:
Automatic segmentationDeep learningGenerative adversarial networksProstate cancer

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Area of Science:

  • Medical image analysis
  • Deep learning in radiology

Background:

  • Deep learning models like Generative Adversarial Networks (GANs) show promise in image translation.
  • U-Net architectures are traditional deep learning models for segmentation tasks.

Purpose of the Study:

  • To investigate if GANs offer a performance boost over U-Net for medical image segmentation with small training datasets.
  • To compare the efficacy of U-Net and conditional GAN (cGAN) models in segmentation tasks with limited data.

Main Methods:

  • Trained U-Net and U-Net with patch discriminator (cGAN) models on varying dataset sizes (1-100 patients).
  • Evaluated segmentation performance for male pelvis CT data using Dice similarity coefficient and Hausdorff distance.
  • Assessed model performance in relation to training dataset size.

Main Results:

  • No significant performance difference was observed between U-Net and cGAN models when trained with identical dataset sizes up to 100 patients.
  • Both models demonstrated significant performance improvements as training dataset size increased from 1 to 20 patients.
  • The size of the training dataset had a more substantial impact on performance than the choice of model architecture.

Conclusions:

  • Conditional GANs did not provide a significant performance advantage over U-Net for the tested segmentation task, even with small datasets.
  • Increasing the training dataset size is crucial for improving segmentation model performance.
  • The study highlights the importance of data quantity over advanced architectures like GANs when dealing with limited medical imaging data.