Coronavirus Disease 2019: Hysteresis Effect of Chest CT and the Correlation with its Severity

Kui Li1, Wei Wang2, Lei Wu3

  • 1Department of Infectious Diseases, Ankang Central Hospital, 85 South Jinzhou Road, Ankang 725000, Shaanxi Province, China.

Current Medical Imaging
|December 21, 2021
PubMed

Insights

Chest CT scans in COVID-19 patients show a hysteresis effect, meaning lung improvements lag behind fever relief. Lower lymphocyte counts and oxygen saturation correlate with increased lung lesion severity.

Area of Science:

  • Medical Imaging
  • Pulmonology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) significantly impacts lung health.
  • Understanding the temporal relationship between clinical recovery and imaging findings is crucial for patient management.

Purpose of the Study:

  • To investigate factors influencing chest computed tomography (CT) hysteresis in COVID-19 patients.
  • To determine the relationship between imaging findings and disease severity.

Main Methods:

  • Retrospective analysis of chest CT data from 166 COVID-19 patients across four hospitals.
  • Assessment of lesion volume and calculation of hysteresis time post-fever relief.
  • Multivariate regression analysis to identify correlations between lung lesions, lymphocyte count, and oxygen saturation.

Main Results:

  • A hysteresis effect was observed, with chest CT improvements lagging behind fever relief.
  • Increased percentage of lesion/total lung volume was associated with decreased peripheral blood lymphocyte count and transcutaneous oxygen saturation.

Conclusions:

  • Pulmonary lesions in COVID-19 exhibit a hysteresis effect relative to fever resolution.
  • Disease severity, indicated by lesion volume, may be linked to reduced lymphocyte counts and oxygen saturation.
Abstract

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