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Updated: Oct 9, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
[SARS-CoV-2 variants: epidemiology, pathophysiology and the importance of vaccines]
Marcelo Bedoya-Sommerkamp1, Jesús Medina-Ranilla1, Víctor Chau-Rodríguez1
1Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima, Perú.
Abstract:
SARS-CoV-2 is a single-stranded RNA virus of the coronavirus family, which causes COVID-19 (Coronavirus Disease 2019). This virus is responsible for the current pandemic, which, since its emergence in late 2019, has caused millions of deaths and has had a global impact not only on public health but also on social and economic areas. Therefore, this article aims to review the most up-to-date information on SARS-CoV-2, beginning with the description of the pathophysiology and phylogenetics of the virus. Also, we will present the emerging SARS-CoV-2 variants, their relevance for local and global public health, their epidemiology in Peru, and finally, the role and importance of vaccines in this context.
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