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δ-Tocopherol derivatives from the leaves of Muntingia calabura L
Truong Nhat Van Do1,2, Tho Huu Le1,2, Hai Xuan Nguyen1,2
1Faculty of Chemistry, University of Science, Ho Chi Minh City, Vietnam.
Abstract:
From an ethyl acetate-soluble fraction of the leaves of Muntingia calabura, one new trimeric δ-tocopherol derivative named as tocomuntin A (1), together with three known δ-tocopherol derivatives (2-4) were isolated. Their structures were elucidated based on the interpretation of NMR and MS spectroscopic data. In this work, δ-tocopherol (3) was found to have α-glucosidase inhibitory activity for the first time (IC50, 47.3 μM).
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