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Published on: November 8, 2015
Monitoring and Managing Cardiovascular Risk in Immune Mediated Inflammatory Diseases
Panagiota Anyfanti1, Athanasia Dara2, Elena Angeloudi1
1Second Medical Department, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Insights
Cardiovascular disease (CVD) is a major concern for patients with immune-mediated inflammatory diseases (IMIDs). This review explores strategies to manage CVD risk in IMIDs, highlighting lifestyle changes and medication awareness.
Area of Science:
- Rheumatology
- Cardiology
- Inflammation
Background:
- Cardiovascular disease (CVD) is highly prevalent in immune-mediated inflammatory diseases (IMIDs).
- Chronic inflammation and traditional risk factors contribute to increased CVD morbidity and mortality in IMID patients.
- Standard CVD risk calculators underestimate risk in IMID populations, necessitating tailored assessment.
Purpose of the Study:
- To provide an overview of current and emerging strategies for CVD risk mitigation in patients with IMIDs.
- To offer a practical approach for managing CVD risk in this vulnerable patient group.
Main Methods:
- Review of current literature on CVD risk in IMIDs.
- Discussion of challenges in CVD risk assessment for IMID patients.
- Exploration of artificial intelligence applications in predictive medicine for CVD.
Main Results:
- Traditional CVD risk calculators are inadequate for IMID patients.
- Behavioral interventions targeting modifiable lifestyle factors are crucial.
- Awareness of antirheumatic medication's impact on CVD risk is essential for rheumatologists.
Conclusions:
- Effective CVD risk management in IMIDs requires a multi-faceted approach.
- Personalized predictive medicine holds future promise but needs validation.
- Integrating lifestyle interventions and careful medication management is key for improving outcomes.
Abstract:
Cardiovascular disease (CVD) is common in immune-mediated inflammatory diseases (IMIDs) and it is predominately attributed to the interplay between chronic inflammation and traditional CVD risk factors. CVD has significant impact on the survival of patients with IMIDs as it is associated with increased morbidity and mortality. Despite recommendations for monitoring and managing CVD in patients with IMIDs, the individual CVD risk assessment remains problematic as CVD risk calculators for the general population consistently underestimate the risk in patients with IMIDs. Application of new technologies utilizing artificial intelligence techniques have shown promising potential for tailoring predictive medicine to the individual patient, but further validation of their role in clinical decision-making is warranted. In the meantime, individuals with IMIDs should be encouraged to adopt behavioral interventions targeting at modifiable lifestyle CVD risk factors, whereas rheumatologists need to be well aware of the unfavorable effects of antirheumatic medication on various CVD risk factors and outcomes. In the current paper, we aim to provide an overview of current and emerging strategies for mitigating CVD risk in patients with IMIDs, based on a practical approach.
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