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Chronic peritoneal dialysis in children with chronic kidney disease: An experience from a North Indian teaching

Karalanglin Tiewsoh1, Akshita Soni1, Lesa Dawman1

  • 1Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of Family Medicine and Primary Care
|December 22, 2021
PubMed

Insights

Chronic peritoneal dialysis (CPD) is a preferred renal replacement therapy for children with end-stage renal disease (ESRD). While effective, infection-related complications and growth issues require careful management in pediatric patients undergoing CPD.

Area of Science:

  • Pediatric Nephrology
  • Renal Replacement Therapy
  • Chronic Kidney Disease Management

Background:

  • Chronic peritoneal dialysis (CPD) is a vital renal replacement therapy (RRT) for pediatric end-stage renal disease (ESRD).
  • Assessing the clinical profile of children initiating CPD in Northern India is crucial for understanding treatment outcomes.

Purpose of the Study:

  • To retrospectively evaluate the clinical characteristics of pediatric patients with chronic kidney disease (CKD) starting CPD.
  • To analyze demographic data, CKD etiology, dialysis methods, and complication rates in this cohort.

Main Methods:

  • Retrospective analysis of 13 pediatric patients with CKD initiated on CPD between 2016 and 2019.
  • Data collected included demographics, CKD causes, catheter insertion, dialysis mode, complications, and catheter survival.

Main Results:

  • The median age for CPD initiation was 92.97 months, with a median serum creatinine of 6.3 mg/dL.
  • A high complication rate of 1 per 5.25 CPD months was observed, including peritonitis (1 episode/13.66 patient-months) and catheter displacement (23%).
  • Median follow-up was 175 days, with the longest being 502 days.

Conclusions:

  • CPD is the preferred RRT modality for young children with ESRD due to challenges with venous access.
  • Infection-related complications and impaired growth are significant concerns in pediatric CPD patients.
Abstract

Keywords:
Childrenchronic kidney diseasechronic peritoneal dialysisperitonitis

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