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The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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Male systemic lupus erythematosus: Two distinct presentations
Sugandhi Akhil1, K Sai Kanth Sharma1, Dharmender Kumar1
1Department of General Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India.
Journal of Family Medicine and Primary Care
|December 22, 2021
Summary
Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting multiple organs. Early diagnosis in males, who are less commonly affected, is crucial for better patient outcomes.
Area of Science:
- Immunology
- Rheumatology
- Autoimmune Diseases
Background:
- Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder.
- Characterized by periods of exacerbations and remissions.
- Autoantibodies target various tissues and organ systems.
Observation:
- Presents two cases of SLE in male patients.
- SLE is diagnosed less frequently in males compared to females.
- Delayed diagnosis in males is often associated with poorer prognoses.
Findings:
- Male SLE patients may present with delayed diagnosis.
- Early detection by primary care physicians can significantly impact outcomes.
- Prompt diagnosis and management are vital for improving patient prognosis.
Implications:
- Highlights the importance of considering SLE in male patients presenting with relevant symptoms.
- Emphasizes the critical role of primary care in the early identification of SLE.
- Suggests that increased physician awareness can lead to improved outcomes for male SLE patients.
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