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Related Concept Videos

Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

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Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

19
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Related Experiment Video

Updated: Oct 9, 2025

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
05:04

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

Published on: September 22, 2023

577

The Use of the "Early Weight Loss Nomograms" as Compared to a Standard Weight Loss Percentage Protocol Will Decrease

Nazmiye Tagi1, Ayla Ergin2, Hulya Selva Bilgen3

  • 1T.R. Ministry of Health İzmir Provincial Health Directorate Bakırçay University Çiğli Training and Research Hospital Yeni Mahalle, İzmir, Turkey.

Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine
|December 22, 2021
PubMed
Summary

The Early Weight Loss Nomograms effectively reduce formula supplementation for newborns. This approach supports higher rates of exclusive breastfeeding, particularly for infants born via cesarean section.

Keywords:
formula supplementationnewborn, breastfeeding“Early Weight Loss Nomograms,”“percentage of daily weight loss,”

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Area of Science:

  • Neonatal care
  • Pediatrics
  • Lactation studies

Background:

  • Newborn weight loss is a critical indicator of infant health and feeding success.
  • Current protocols for managing neonatal weight loss vary, potentially impacting breastfeeding rates.
  • The "Early Weight Loss Nomograms" offer a standardized approach to assess infant weight changes.

Purpose of the Study:

  • To compare the incidence of formula supplementation using the "Early Weight Loss Nomograms" versus a "weight loss percentage" protocol.
  • To evaluate the impact of each management strategy on exclusive breastfeeding rates in newborns.
  • To identify the most effective method for monitoring neonatal weight loss and supporting breastfeeding.

Main Methods:

  • A cohort of 308 newborns was studied.
  • Formula supplementation was administered based on the "Early Weight Loss Nomograms" (exceeding the 95th percentile).
  • A hypothetical "weight loss percentage" protocol was applied for comparison, defining pathological weight loss as >5% at 24 hours or >8% at 48 hours.

Main Results:

  • Mean postnatal weight loss was significantly higher in infants born via cesarean section compared to vaginal deliveries.
  • Using the nomograms, exclusive breastfeeding rates were high (89.4% vaginal, 89.2% cesarean).
  • The "weight loss percentage" protocol would have significantly reduced exclusive breastfeeding rates for cesarean-born infants (64.2% vs. 89.2%).

Conclusions:

  • The "Early Weight Loss Nomograms" are effective in minimizing formula supplementation.
  • This nomogram-based approach supports higher rates of exclusive breastfeeding.
  • Implementing the "Early Weight Loss Nomograms" is recommended for neonatal care to promote successful breastfeeding.