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Related Experiment Videos

Trigeminal neuralgia and multiple sclerosis.

R Brisman

    Archives of Neurology
    |April 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Radiofrequency electrocoagulation effectively treats trigeminal neuralgia (TN). Patients with TN and multiple sclerosis (TNMS) experienced similar recurrence rates to those with TN alone, despite differences in age and pain presentation.

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    Area of Science:

    • Neurosurgery
    • Neurology
    • Pain Management

    Background:

    • Trigeminal neuralgia (TN) is a debilitating facial pain condition.
    • Radiofrequency electrocoagulation is a treatment option for TN.
    • The impact of multiple sclerosis (MS) on TN treatment outcomes is not fully understood.

    Purpose of the Study:

    • To compare the outcomes of radiofrequency electrocoagulation in patients with TN and MS (TNMS) versus those with TN alone.
    • To identify demographic and clinical differences between TNMS and non-MS TN patients.
    • To assess the long-term recurrence rates of TN after radiofrequency electrocoagulation in both groups.

    Main Methods:

    • Retrospective analysis of 16 patients with TNMS and 219 patients with TN without MS.
    • Treatment involved radiofrequency electrocoagulation of the gasserian ganglion and retrogasserian rootlets, with or without glycerol.

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  • Kaplan-Meier product-limit estimates were used to calculate ipsilateral recurrence probability.

    • Main Results:

    • Patients with TNMS were younger than those with TN alone.
    • Bilateral facial pain was more common in the TNMS group.
    • No significant difference in the probability of ipsilateral TN recurrence was observed between the TNMS and non-MS TN groups.

    Conclusions:

    • Radiofrequency electrocoagulation is a viable treatment for TN, regardless of MS comorbidity.
    • While TNMS patients present with distinct demographic and pain characteristics, long-term pain recurrence rates are comparable to non-MS TN patients.
    • This suggests MS does not negatively impact the efficacy of radiofrequency electrocoagulation for trigeminal neuralgia.