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Dissociative Disorders

Dissociative Disorders

Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
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Brain Waves

Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:

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Related Experiment Video

Updated: Oct 9, 2025

EEG Mu Rhythm in Typical and Atypical Development

EEG Mu Rhythm in Typical and Atypical Development

Published on: April 9, 2014

Dissociation and Brain Rhythms: Pitfalls and Promises.

Tineke Grent-'t-Jong^1,2, Lucia Melloni^3,4, Peter J Uhlhaas^1,2

¹Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.

Frontiers in Psychiatry

|December 23, 2021

Summary

Researchers identified a specific brain rhythm linked to dissociation. This study reviews the findings and discusses challenges in connecting brain circuits to complex psychiatric conditions.

Keywords:

animal models dissociation ketamine neural oscillations optogenetics translational neuroscience

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Last Updated: Oct 9, 2025

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Dissociation of the Confounding Influences of Expectancy and Integrative Difficulty Residing in Anomalous Sentences in Event-related Potential Studies

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Area of Science:

Neuroscience
Psychiatry
Computational Neuroscience

Background:

Dissociative states are complex phenomena often observed in psychiatric disorders.
Understanding the neural underpinnings of dissociation is crucial for developing effective treatments.
Recent research has proposed specific circuit mechanisms for dissociative states.

Purpose of the Study:

To critically review the proposed circuit mechanism for dissociative states.
To contextualize findings within the existing human literature on dissociation.
To highlight challenges in translational neuroscience for linking brain circuits to psychiatric phenotypes.

Main Methods:

Optogenetics and pharmacology in mice.
Intracranial recordings and electrical stimulation in an epilepsy patient.
Review of human literature on dissociation.

Main Results:

Identification of a posteromedial cortical delta-rhythm underlying dissociation.
The proposed mechanism links a specific neural rhythm to a complex behavioral state.
The study acknowledges limitations and challenges in translational research.

Conclusions:

The proposed posteromedial cortical delta-rhythm offers a potential neural correlate for dissociation.
Translating findings from animal models to human psychiatric conditions presents significant challenges.
Further research is needed to bridge the gap between circuit mechanisms and complex behavioral phenotypes.